Patterns of intra-and inter-tumor phenotypic heterogeneity in lethal prostate cancer
Martine P Roudier, Roman Gulati, Erolcan Sayar, Radhika A Patel, Micah Tratt, Helen M Richards, Paloma Cejas, Miguel Munoz Gomez, Xintao Qiu, Yingtian Xie, Brian Hanratty, Samir Zaidi, Jimmy L Zhao, Mohamed Adil, Chitvan Mittal, Yibai Zhao, Ruth Dumpit, Ilsa Coleman, Jin-Yih Low, Thomas Persse, Patricia C Galipeau, John K Lee, Maria Tretiakova, Meagan Chambers, Funda Vakar-Lopez, Lawrence D True, Marie Perrone, Hung-Ming Lam, Lori A Kollath, Chien-Kuang C Ding, Stephanie Harmon, Heather H Cheng, Evan Y Yu, Robert B Montgomery, Jessica E Hawley, Daniel W Lin, Eva Corey, Michael T Schweizer, Manu Setty, Gavin Ha, Charles L Sawyers, Colm Morrissey, Henry W Long, Peter S Nelson, Michael C Haffner
The Journal of Clinical Investigation,
2025
Molecular Imaging of Androgen Receptor Expression and Glycolysis as Biomarkers for Clinical Outcome for Metastatic Castration–Resistant Prostate Cancer
Samir Zaidi, Jessica Flynn, Josef J Fox, Andreas G Wibmer, Glenn Heller, Howard I Scher, Steven M Larson, Michael J Morris
Mutations in 329 probands with suspected renal electrolyte disorders
Renan Eduardo Aparicio, Sheng Chih Jin, Weilai Dong, Samir Zaidi, Michael C Sierant, James Knight, Robert D Bjornson, Christopher Castaldi, Shrikant M Mane, Thomas M Kaneko, Carol Nelson-Williams, Richard P Lifton
Organocatalytic asymmetric tandem reaction for the enantioselective synthesis of chiral oxindoles to construct CyK dyes
Le Wang, Zi-Hao Li, Di Wu, Rui-Tian Ge, Jia Zhou, Yin-Feng Zhang, Shu-Yu Zhang
A phase 1b/2 study evaluating the activity of tinengotinib in combination with androgen receptor pathway inhibitors (ARPIs) in patients with metastatic castration resistant prostate cancer (mCRPC)
Wassim Abida, Yu Chen, Deaglan Joseph McHugh, Michael J Morris, Frank Wu, Peng Peng, Katie Hennessy, Hui Wang, Jean Fan, Samir Zaidi
Journal of Clinical Oncology,
2025
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1
Romero R, Chu T, González Robles TJ, Smith P, Xie Y, Kaur H, Yoder S, Zhao H, Mao C, Kang W, Pulina MV, Lawrence KE, Gopalan A, Zaidi S, Yoo K, Choi J, Fan N, Gerstner O, Karthaus WR, DeStanchina E, Ruggles KV, Westcott PMK, Chaligné R, Pe'er D, Sawyers CL.
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation
Quintanal-Villalonga A, Kawasaki K, Redin E, Uddin F, Rakhade S, Durani V, Sabet A, Shafer M, Karthaus WR, Zaidi S, Zhan YA, Manoj P, Sridhar H, Kinyua D, Zhong H, Mello BP, Ciampricotti M, Bhanot UK, Linkov I, Qiu J, Patel RA, Morrissey C, Mehta S, Barnes J, Haffner MC, Socci ND, Koche RP, de Stanchina E, Molina-Pinelo S, Salehi S, Yu HA, Chan JM, Rudin CM.
Signal Transduct Target Therapy,
2024
Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen-targeted therapies
Zaidi S, Park J, Chan JM, Roudier MP, Zhao JL, Gopalan A, Wadosky KM, Patel RA, Sayar E, Karthaus WR, Kates DH, Chaudhary O, Xu T, Masilionis I, Mazutis L, Chaligné R, Obradovic A, Linkov I, Barlas A, Jungbluth AA, Rekhtman N, Silber J, Manova-Todorova K, Watson PA, True LD, Morrissey C, Scher HI, Rathkopf DE, Morris MJ, Goodrich DW, Choi J, Nelson PS, Haffner MC, Sawyers CL.
Proc Natl Acad Sci U S A,
2024
Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies
Zaidi S, Park J, Chan JM, Roudier MP, Zhao JL, Gopalan A, Wadosky KM, Patel RA, Sayar E, Karthaus WR, Kates DH, Chaudhary O, Xu T, Masilionis I, Mazutis L, Chaligné R, Obradovic A, Linkov I, Barlas A, Jungbluth AA, Rekhtman N, Silber J, Manova-Todorova K, Watson PA, True LD, Morrissey C, Scher HI, Rathkopf DE, Morris MJ, Goodrich DW, Choi J, Nelson PS, Haffner MC, Sawyers CL.
CEACAM5-Targeted Immuno-PET in Androgen Receptor-Negative Prostate Cancer
Imberti C, De Gregorio R, Korsen JA, Hoang TT, Khitrov S, Kalidindi T, Nandakumar S, Park J, Zaidi S, Pillarsetty NVK, Lewis JS.
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates
Ajkunic A, Sayar E, Roudier MP, Patel RA, Coleman IM, De Sarkar N, Hanratty B, Adil M, Zhao J, Zaidi S, True LD, Sperger JM, Cheng HH, Yu EY, Montgomery RB, Hawley JE, Ha G, Persse T, Galipeau P, Lee JK, Harmon SA, Corey E, Lang JM, Sawyers CL, Morrissey C, Schweizer MT, Gulati R, Nelson PS, Haffner MC.
Understanding osteokine biology
Zaidi M, Zaidi S, Yuen T.
